Implementación de tecnología NFC en el canal HORECA: sostenibilidad, fidelización y definición del perfil del usuario

Achieving an inclusive digital and sustainable transition incorporating all agents of society is one of the most significant challenges facing contemporary societies. However, in the last decade, initiatives that seek to increase sustainability through new technologies have multiplied. This article will analyze the creative process and the results of using FastVisit, an application for the hospitality industry that replaces paper tickets with electronic ones. In addition, this technology records the consumption profile of customers. The results show the application's effectiveness for adopting new technologies in small and medium-sized enterprises and digital migration.El reto de realizar un transición digital y sostenible inclusiva, que incorpore a todos los agentes de la sociedad, es uno de los mayores desafíos de las sociedades contemporáneas. Sin embargo, en la última década se han multiplicado las iniciativas que persiguen aumentar la sostenibilidad por medio del uso de las nuevas tecnologías. En este artículo se analizará el proceso de creación y los resultados del uso de FastVisit, una aplicación, para el ámbito de la hostelería, en el que substituye el ticket en papel por uno electrónico. Además, esta tecnología registra el perfil de consumo de los clientes. Los resultados muestran la efectividad de la aplicación para la adaptación de las nuevas tecnologías en las pequeñas y medianas empresas y la migración digital

Physical exercise shapes the mouse brain epigenome

[Objective]: To analyze the genome-wide epigenomic and transcriptomic changes induced by long term resistance or endurance training in the hippocampus of wild-type mice.[Methods]: We performed whole-genome bisulfite sequencing (WGBS) and RNA sequencing (RNA-seq) of mice hippocampus after 4 weeks of specific training. In addition, we used a novel object recognition test before and after the intervention to determine whether the exercise led to an improvement in cognitive function.[Results]: Although the majority of DNA methylation changes identified in this study were training-model specific, most were associated with hypomethylation and were enriched in similar histone marks, chromatin states, and transcription factor biding sites. It is worth highlighting the significant association found between the loss of DNA methylation in Tet1 binding sites and gene expression changes, indicating the importance of these epigenomic changes in transcriptional regulation. However, endurance and resistance training activate different gene pathways, those being associated with neuroplasticity in the case of endurance exercise, and interferon response pathways in the case of resistance exercise, which also appears to be associated with improved learning and memory functions.[Conclusions]: Our results help both understand the molecular mechanisms by which different exercise models exert beneficial effects for brain health and provide new potential therapeutic targets for future research.This work was supported by the Spanish Association Against Cancer (PROYE18061FERN to M.F.F.), the Asturias Government (PCTI) co-funding 2018-2022/FEDER (IDI/2018/146 to M.F.F.), the Fundación General CSIC (0348_CIE_6_E to M.F.F.), the Health Institute Carlos III (Plan Nacional de I+D+I) co-funding FEDER (PI18/01527 to M.F.F and A.F.F.), the MINECO (DEP2015-69980-P to B.F.G.), and the Fundación Tatiana Pérez de Guzmán el Bueno (“Ayudas a Proyectos de Investigación en Neurociencia-2020” to C.T.Z and E.I.G.). R.G.U. is supported by the Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER). J.R.T. is supported by a Juan de la Cierva fellowship from the Spanish Ministry of Science and Innovation MCIN/AEI /10.13039/501100011033 (IJC2018-036825-I). R.F.P. is supported by the Severo Ochoa program (BP17-114). P.P.H. is supported by Ayudas para la realización de Tesis Doctorales. Modalidad A fellowship from the University of Oviedo (PAPI-20-PF-19). We also acknowledge support from the IUOPA-ISPA-FINBA (the IUOPA is supported by the Obra Social Cajastur-Liberbank, Spain).Peer reviewe

Installation and simulation of a cyclohexane plant in Argentina

Grado en Ingeniería Químic

La escuela infantil : un lugar de encuentro entre culturas

Se incluyen anexos con posibles actividades para realizar con alumnos y con familias de cultura gitana, latinoamericana, china o musulmanaLa finalidad del proyecto es que la comunidad educativa del centro, y el propio barrio, tome conciencia del entorno intercultural en el que están inmersos. Se trata de que cada familia pueda dar a conocer su cultura y hacer partícipes a los demás de sus costumbres y vivencias. Los objetivos son que participen las instituciones del barrio como la asociación de vecinos o la Junta Municipal; abrir la escuela a todas las culturas; aprovechar el hecho multicultural para que sea enriquecedor para todos; y sentar las bases de una futura convivencia basada en valores democráticos. El proyecto comienza con la transmisión, en el aula, de cada una de las culturas a todos los alumnos. Para ello, se confeccionan murales y listados de las diferentes nacionalidades; se exponen fotografías; se realizan talleres y jornadas interculturales de música, danza, teatro o cuentacuentos; y se crea un fondo documental sobre la interculturalidad. Otras actividades son la celebración del año chino, los carnavales o las navidades interculturales. Para finalizar, se celebra una fiesta representativa de cada cultura en la que participan las familias y donde se abren las puertas a todo el barrio.Madrid (Comunidad Autónoma). Consejería de Educación. Dirección General de Ordenación AcadémicaMadridMadrid (Comunidad Autónoma). Subdirección General de Formación del Profesorado. CRIF Las Acacias; General Ricardos 179 - 28025 Madrid; Tel. + 34915250893ES

Diagonal Cero - Número 14

Textos: Poemas de Saúl Yurkievich, Delchis Girotti, Edgardo Vigo, Omar Gancedo. Grupo de poetas letristas, por Edgardo Vigo. Pequeña antología de poesía uruguaya, poemas de: Roberto Sienra, Tabaré Rivas Mencia, Ariel Davison Vigil, Raúl Pisano Guido, Miguel Ángel Olivera, Horacio Ferrer Vila, Juan Carlos Tajes. Selección poética de Victor García Robles, presentación de Ruben Natale. Segunda pequeña antología do bolsillo de poetas mexicanos, poemas de: Sergio Mondragón, Roberto Fernández Iglesias, Guillermo Fernandez, Thelma Nava, Manuel Quiñones Hernández, Gustavo Pliego. Grupo de poesía La Plata, poemas de: Carlos Imelnitzky, Mónica Bó, Ernesto Defani, Felipe Martínez Pérez, Imar Miguel Lamonega, Sandra Filippi, Gerardo Mario Gologoff, Trabajos plásticos Edgardo Vigo. Ricardo Mampaey. Jorge Casteran. Bertini.Centro de Arte Experimental Vig

Diagonal Cero - Número 14

Textos: Poemas de Saúl Yurkievich, Delchis Girotti, Edgardo Vigo, Omar Gancedo. Grupo de poetas letristas, por Edgardo Vigo. Pequeña antología de poesía uruguaya, poemas de: Roberto Sienra, Tabaré Rivas Mencia, Ariel Davison Vigil, Raúl Pisano Guido, Miguel Ángel Olivera, Horacio Ferrer Vila, Juan Carlos Tajes. Selección poética de Victor García Robles, presentación de Ruben Natale. Segunda pequeña antología do bolsillo de poetas mexicanos, poemas de: Sergio Mondragón, Roberto Fernández Iglesias, Guillermo Fernandez, Thelma Nava, Manuel Quiñones Hernández, Gustavo Pliego. Grupo de poesía La Plata, poemas de: Carlos Imelnitzky, Mónica Bó, Ernesto Defani, Felipe Martínez Pérez, Imar Miguel Lamonega, Sandra Filippi, Gerardo Mario Gologoff, Trabajos plásticos Edgardo Vigo. Ricardo Mampaey. Jorge Casteran. Bertini.Centro de Arte Experimental Vig

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

Background Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

International audienceBackground: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0-4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2-6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society